Varaico: Literature-Extracted Genetic Variants

Gene:PLK2
Variant:p.K111R

PLK2

162 papers

RefSeq Summary

The protein encoded by this gene is a member of the polo family of serine/threonine protein kinases that have a role in normal cell division. This gene is most abundantly expressed in testis, spleen a...

Pfam Domains

Pkinaseaa 68–320UCSCProtein kinase domain
POLO_boxaa 498–555UCSCPOLO box duplicated region
POLO_boxaa 594–659UCSCPOLO box duplicated region

Gene Aliases

HGNC Name

polo like kinase 2

HGNC Alias Symbol

SNK

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
3 papers
NM_006622.4
p.K111R
c.332A>G
Surrounding Variants
1 paper
NM_006622.4
p.A109V
c.326C>T
1 paper
NM_006622.4
p.I113I
c.339T>C
1 paper
NM_006622.4
p.S116R
c.346A>C
1 paper
NM_006622.4
p.S116R
c.348C>G
1 paper
NM_006622.4
p.S116R
c.348C>A
1 paper
NM_006622.4
p.K126T
c.377A>C
1 paper
NM_006622.4
p.K126N
c.378G>T
1 paper
NM_006622.4
p.K126N
c.378G>C
2 papers
NM_006622.4
p.K126_I127Splc
c.378+4C>T
1 paper
NM_006622.4
p.G92G
c.276C>T
1 paper
NM_006622.4
p.G92C
c.274G>T
4 papers
NM_006622.4
p.G92S
c.274G>A
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