Varaico: Literature-Extracted Genetic Variants

Gene:PLK2
Variant:p.E68D

PLK2

162 papers

RefSeq Summary

The protein encoded by this gene is a member of the polo family of serine/threonine protein kinases that have a role in normal cell division. This gene is most abundantly expressed in testis, spleen a...

Pfam Domains

Pkinaseaa 68–320UCSCProtein kinase domain
POLO_boxaa 498–555UCSCPOLO box duplicated region
POLO_boxaa 594–659UCSCPOLO box duplicated region

Gene Aliases

HGNC Name

polo like kinase 2

HGNC Alias Symbol

SNK

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
3 papers
NM_006622.4
p.E68D
c.204G>C
Surrounding Variants
3 papers
NM_006622.4
p.E68D
c.204G>T
1 paper
NM_006622.4
p.I69delFs
c.207delG
1 paper
NM_006622.4
p.I73V
c.217A>G
1 paper
NM_006622.4
p.H62Q
c.186T>A
6 papers
NM_006622.4
p.H60D
c.178C>G
1 paper
NM_006622.4
p.H59Q
c.177T>A
1 paper
NM_006622.4
p.V87E
c.260T>A
1 paper
NM_006622.4
p.K90E
c.268A>G
1 paper
NM_006622.4
p.K90R
c.269A>G
1 paper
NM_006622.4
p.P44S
c.130C>T
1 paper
NM_006622.4
p.Q43E
c.127C>G
1 paper
NM_006622.4
p.S30W
c.89C>G
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