Varaico: Literature-Extracted Genetic Variants

Gene:PLK2
Variant:p.R5W

PLK2

162 papers

RefSeq Summary

The protein encoded by this gene is a member of the polo family of serine/threonine protein kinases that have a role in normal cell division. This gene is most abundantly expressed in testis, spleen a...

Pfam Domains

Pkinaseaa 68–320UCSCProtein kinase domain
POLO_boxaa 498–555UCSCPOLO box duplicated region
POLO_boxaa 594–659UCSCPOLO box duplicated region

Gene Aliases

HGNC Name

polo like kinase 2

HGNC Alias Symbol

SNK

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
2 papers
NM_006622.4
p.R5W
c.13C>T
Surrounding Variants
1 paper
NM_006622.4
p.L4F
c.12G>C
1 paper
NM_006622.4
p.I7F
c.19A>T
1 paper
NM_006622.4
p.M1I
c.3G>A
1 paper
NM_006622.4
p.M1R
c.2T>G
1 paper
NM_006622.4
p.Y9H
c.25T>C
1 paper
NM_006622.4
p.A12T
c.34G>A
1 paper
NM_006622.4
p.Q20H
c.60G>C
1 paper
NM_006622.4
p.L22P
c.65T>C
1 paper
NM_006622.4
p.L22del1
c.64_65delCAG
1 paper
NM_006622.4
p.G23D
c.68G>A
1 paper
NM_006622.4
p.G25G
c.75T>A
1 paper
NM_006622.4
p.A28S
c.82G>T
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