Varaico: Literature-Extracted Genetic Variants

Gene:PLK3
Variant:p.G72V

PLK3

136 papers

RefSeq Summary

The protein encoded by this gene is a member of the highly conserved polo-like kinase family of serine/threonine kinases. Members of this family are characterized by an amino-terminal kinase domain an...

Pfam Domains

Pkinaseaa 62–314UCSCProtein kinase domain
POLO_boxaa 472–529UCSCPOLO box duplicated region
POLO_boxaa 569–633UCSCPOLO box duplicated region

Gene Aliases

HGNC Name

polo like kinase 3

HGNC Previous Symbol

CNK

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_004073.4
p.G72V
c.215G>T
Surrounding Variants
1 paper
NM_004073.4
p.F73F
c.219C>T
1 paper
NM_004073.4
p.T82A
c.244A>G
1 paper
NM_004073.4
p.T84A
c.250A>G
3 papers
NM_004073.4
p.K91R
c.272A>G
1 paper
NM_004073.4
p.Q103E
c.307C>G
1 paper
NM_004073.4
p.K106_I107Splc
c.318+1G>A
1 paper
NM_004073.4
p.I122M
c.366C>G
1 paper
NM_004073.4
p.V123M
c.367G>A
1 paper
NM_004073.4
p.R124S
c.370C>A
5 papers
NM_004073.4
p.R124H
c.371G>A
2 papers
NM_004073.4
p.R124L
c.371G>T
1 paper
NM_004073.4
p.S126*
c.377C>A
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