Varaico: Literature-Extracted Genetic Variants

Gene:PLK3
Variant:p.Q178E

PLK3

136 papers

RefSeq Summary

The protein encoded by this gene is a member of the highly conserved polo-like kinase family of serine/threonine kinases. Members of this family are characterized by an amino-terminal kinase domain an...

Pfam Domains

Pkinaseaa 62–314UCSCProtein kinase domain
POLO_boxaa 472–529UCSCPOLO box duplicated region
POLO_boxaa 569–633UCSCPOLO box duplicated region

Gene Aliases

HGNC Name

polo like kinase 3

HGNC Previous Symbol

CNK

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
2 papers
NM_004073.4
p.Q178E
c.532C>G
Surrounding Variants
1 paper
NM_004073.4
p.R179C
c.535C>T
1 paper
NM_004073.4
p.Q168*
c.502C>T
1 paper
NM_004073.4
p.W151S
c.452G>C
1 paper
NM_004073.4
p.A148A
c.444C>A
1 paper
NM_004073.4
p.D203V
c.608A>T
1 paper
NM_004073.4
p.P212T
c.634C>A
1 paper
NM_004073.4
p.S143N
c.428G>A
1 paper
NM_004073.4
p.D133D
c.399C>T
1 paper
NM_004073.4
p.S126*
c.377C>A
5 papers
NM_004073.4
p.R124H
c.371G>A
2 papers
NM_004073.4
p.R124L
c.371G>T
1 paper
NM_004073.4
p.R124S
c.370C>A
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