Varaico: Literature-Extracted Genetic Variants

Gene:PLK3
Variant:p.T262M

PLK3

136 papers

RefSeq Summary

The protein encoded by this gene is a member of the highly conserved polo-like kinase family of serine/threonine kinases. Members of this family are characterized by an amino-terminal kinase domain an...

Pfam Domains

Pkinaseaa 62–314UCSCProtein kinase domain
POLO_boxaa 472–529UCSCPOLO box duplicated region
POLO_boxaa 569–633UCSCPOLO box duplicated region

Gene Aliases

HGNC Name

polo like kinase 3

HGNC Previous Symbol

CNK

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_004073.4
p.T262M
c.785C>T
Surrounding Variants
1 paper
NM_004073.4
p.D264N
c.790G>A
1 paper
NM_004073.4
p.P259S
c.775C>T
1 paper
NM_004073.4
p.T268M
c.803C>T
1 paper
NM_004073.4
p.G256R
c.766G>A
1 paper
NM_004073.4
p.G256R
c.766G>C
1 paper
NM_004073.4
p.R270H
c.809G>A
1 paper
NM_004073.4
p.T252M
c.755C>T
1 paper
NM_004073.4
p.L283F
c.847C>T
1 paper
NM_004073.4
p.L285P
c.854T>C
2 papers
NM_004073.4
p.R300Q
c.899G>A
1 paper
NM_004073.4
p.R310H
c.929G>A
1 paper
NM_004073.4
p.D242A
c.725A>C
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