Varaico: Literature-Extracted Genetic Variants

Gene:PLK3
Variant:p.K316_G317Splc

PLK3

136 papers

RefSeq Summary

The protein encoded by this gene is a member of the highly conserved polo-like kinase family of serine/threonine kinases. Members of this family are characterized by an amino-terminal kinase domain an...

Pfam Domains

Pkinaseaa 62–314UCSCProtein kinase domain
POLO_boxaa 472–529UCSCPOLO box duplicated region
POLO_boxaa 569–633UCSCPOLO box duplicated region

Gene Aliases

HGNC Name

polo like kinase 3

HGNC Previous Symbol

CNK

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_004073.4
p.K316_G317Splc
c.949-10C>T
Surrounding Variants
1 paper
NM_004073.4
p.G317R
c.949G>C
1 paper
NM_004073.4
p.Y318D
c.952T>G
1 paper
NM_004073.4
p.D321N
c.961G>A
1 paper
NM_004073.4
p.C328C
c.984C>T
1 paper
NM_004073.4
p.T330I
c.989C>T
2 papers
NM_004073.4
p.P337delFs
c.1011delC
2 papers
NM_004073.4
p.P336fs
c.1006_1007fs
1 paper
NM_004073.4
p.N338fs
c.1012_1013fs
1 paper
NM_004073.4
p.K316N
c.948G>C
1 paper
NM_004073.4
p.K316N
c.948G>T
1 paper
NM_004073.4
p.R354K
c.1061G>A
1 paper
NM_004073.4
p.R310H
c.929G>A
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