Varaico: Literature-Extracted Genetic Variants

Gene:PLK3
Variant:p.D642Y

PLK3

136 papers

RefSeq Summary

The protein encoded by this gene is a member of the highly conserved polo-like kinase family of serine/threonine kinases. Members of this family are characterized by an amino-terminal kinase domain an...

Pfam Domains

Pkinaseaa 62–314UCSCProtein kinase domain
POLO_boxaa 472–529UCSCPOLO box duplicated region
POLO_boxaa 569–633UCSCPOLO box duplicated region

Gene Aliases

HGNC Name

polo like kinase 3

HGNC Previous Symbol

CNK

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_004073.4
p.D642Y
c.1924G>T
Surrounding Variants
1 paper
NM_004073.4
p.R641W
c.1921C>T
2 papers
NM_004073.4
p.R643H
c.1928G>A
1 paper
NM_004073.4
p.R638H
c.1913G>A
1 paper
NM_004073.4
p.R634C
c.1900C>T
2 papers
NM_004073.4
p.T614I
c.1841C>T
4 papers
NM_004073.4
p.R610H
c.1829G>A
1 paper
NM_004073.4
p.Q583_V584Splc
c.1749+46G>A
1 paper
NM_004073.4
p.A572P
c.1714G>C
1 paper
NM_004073.4
p.T569M
c.1706C>T
1 paper
NM_004073.4
p.P561P
c.1683C>T
1 paper
NM_004073.4
p.E553fs
c.1657_1658fs
1 paper
NM_004073.4
p.E553_E554delFs
c.1658_1661del4
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