Varaico: Literature-Extracted Genetic Variants

PLXNA2

595 papers

RefSeq Summary

This gene encodes a member of the plexin-A family of semaphorin co-receptors. Semaphorins are a large family of secreted or membrane-bound proteins that mediate repulsive effects on axon pathfinding d...

Pfam Domains

Semaaa 310–489UCSCSema domain

PSIaa 510–560UCSCPlexin repeat

TIG_plexinaa 565–654UCSCTIG domain

PSIaa 655–702UCSCPlexin repeat

TIG_2aa 708–802UCSCTIG domain found in plexin

PSIaa 803–856UCSCPlexin repeat

Gene Aliases

HGNC Name

plexin A2

HGNC Previous Symbol

PLXN2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_025179.4

p.A61G

c.182C>G

Surrounding Variants

1 paper

NM_025179.4

p.A61V

c.182C>T

1 paper

NM_025179.4

p.A61A

c.183C>T

1 paper

NM_025179.4

p.T59M

c.176C>T

2 papers

NM_025179.4

p.T59A

c.175A>G

1 paper

NM_025179.4

p.G58G

c.174G>C

4 papers

NM_025179.4

p.Q57R

c.170A>G

2 papers

NM_025179.4

p.A66T

c.196G>A

1 paper

NM_025179.4

p.A66V

c.197C>T

2 papers

NM_025179.4

p.V55I

c.163G>A

1 paper

NM_025179.4

p.N68D

c.202A>G

1 paper

NM_025179.4

p.R69W

c.205C>T

1 paper

NM_025179.4

p.N51S

c.152A>G