Varaico: Literature-Extracted Genetic Variants

PLXNA2

595 papers

RefSeq Summary

This gene encodes a member of the plexin-A family of semaphorin co-receptors. Semaphorins are a large family of secreted or membrane-bound proteins that mediate repulsive effects on axon pathfinding d...

Pfam Domains

Semaaa 310–489UCSCSema domain

PSIaa 510–560UCSCPlexin repeat

TIG_plexinaa 565–654UCSCTIG domain

PSIaa 655–702UCSCPlexin repeat

TIG_2aa 708–802UCSCTIG domain found in plexin

PSIaa 803–856UCSCPlexin repeat

Gene Aliases

HGNC Name

plexin A2

HGNC Previous Symbol

PLXN2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_025179.4

p.S22S

c.66A>T

Surrounding Variants

1 paper

NM_025179.4

p.L21V

c.61C>G

1 paper

NM_025179.4

p.L21I

c.61C>A

2 papers

NM_025179.4

p.L20Q

c.59T>A

1 paper

NM_025179.4

p.W25*

c.74G>A

1 paper

NM_025179.4

p.L20V

c.58C>G

1 paper

NM_025179.4

p.W25*

c.75G>A

1 paper

NM_025179.4

p.V13V

c.39G>C

1 paper

NM_025179.4

p.P31delFs

c.92delG

1 paper

NM_025179.4

p.A32G

c.95C>G

1 paper

NM_025179.4

p.E12K

c.34G>A

2 papers

NM_025179.4

p.A33_G34insFs

c.99_100insT

1 paper

NM_025179.4

p.G34A

c.101G>C