prostate transmembrane protein, androgen induced 1

TMEPAI

transmembrane, prostate androgen induced RNA

solid tumor-associated gene 1

Protein TMEPAI

Prostate transmembrane protein androgen induced 1

Solid tumor-associated 1 protein

Transmembrane prostate androgen-induced protein

This gene encodes a transmembrane protein that contains a Smad interacting motif (SIM). Expression of this gene is induced by androgens and transforming growth factor beta, and the encoded protein suppresses the androgen receptor and transforming growth factor beta signaling pathways though interactions with Smad proteins. Overexpression of this gene may play a role in multiple types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011].

Varaico: Literature-Extracted Genetic Variants

PMEPA1

RefSeq Summary

Pfam Domains

Gene Aliases

HGNC Name

HGNC Previous Symbol