Varaico: Literature-Extracted Genetic Variants

POLD2

52 papers

RefSeq Summary

This gene encodes the 50-kDa catalytic subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication an...

Pfam Domains

DNA_pol_D_Naa 49–176UCSCDNA polymerase delta subunit OB-fold domain

DNA_pol_D_Naa 84–211UCSCDNA polymerase delta subunit OB-fold domain

DNA_pol_E_Baa 196–412UCSCDNA polymerase alpha/epsilon subunit B

Gene Aliases

HGNC Name

DNA polymerase delta 2, accessory subunit

HGNC Previous Names

polymerase (DNA directed), delta 2, regulatory subunit (50kD); polymerase (DNA directed), delta 2, regulatory subunit 50kDa; polymerase (DNA) delta 2, accessory subunit

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006230.4

p.N406S

c.1217A>G