Varaico: Literature-Extracted Genetic Variants

Gene:POLD3
Variant:p.I20_V21Splc

POLD3

203 papers

RefSeq Summary

This gene encodes the 66-kDa subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. ...

Pfam Domains

CDC27aa 19–466UCSCDNA polymerase subunit Cdc27

Gene Aliases

HGNC Name

DNA polymerase delta 3, accessory subunit

HGNC Alias Symbols

P66; KIAA0039; P68; PPP1R128

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
3 papers
NM_006591.3
p.I20_V21Splc
c.61-2A>G
Surrounding Variants
1 paper
NM_006591.3
p.K24R
c.71A>G
1 paper
NM_006591.3
p.W25*
c.74G>A
1 paper
NM_006591.3
p.W25*
c.75G>A
1 paper
NM_006591.3
p.L26insFs
c.77dupT
1 paper
NM_006591.3
p.L26P
c.77T>C
1 paper
NM_006591.3
p.S27R
c.79A>C
1 paper
NM_006591.3
p.G31G
c.93G>C
1 paper
NM_006591.3
p.V32G
c.95T>G
1 paper
NM_006591.3
p.V32V
c.96T>A
3 papers
NM_006591.3
p.I20_V21Splc
c.60+1G>C
4 papers
NM_006591.3
p.I10T
c.29T>C
1 paper
NM_006591.3
p.Y6_L7insTA
c.16_20ins6
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."