Varaico: Literature-Extracted Genetic Variants

Gene:POLE4
Variant:p.Q61H

POLE4

209 papers

RefSeq Summary

POLE4 is a histone-fold protein that interacts with other histone-fold proteins to bind DNA in a sequence-independent manner. These histone-fold protein dimers combine within larger enzymatic complexe...

Pfam Domains

CBFD_NFYB_HMFaa 39–103UCSCHistone-like transcription factor (CBF/NF-Y) and archaeal histone

Gene Aliases

HGNC Name

DNA polymerase epsilon 4, accessory subunit

HGNC Alias Symbol

p12

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_019896.4
p.Q61H
c.183G>T
Surrounding Variants
1 paper
NM_019896.4
p.Q61H
c.183G>C
1 paper
NM_019896.4
p.Q61R
c.182A>G
1 paper
NM_019896.4
p.Q61K
c.181C>A
2 papers
NM_019896.4
p.A63P
c.187G>C
2 papers
NM_019896.4
p.G60R
c.178G>A
1 paper
NM_019896.4
p.I64_F65insG
c.190_194ins3
3 papers
NM_019896.4
p.A59delFs
c.176delC
1 paper
NM_019896.4
p.I66_L67delFs
c.196_199del4
1 paper
NM_019896.4
p.L58L
c.172C>T
1 paper
NM_019896.4
p.L58delFs
c.173delT
1 paper
NM_019896.4
p.V56M
c.166G>A
1 paper
NM_019896.4
p.L67R
c.200T>G
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