Varaico: Literature-Extracted Genetic Variants

Gene:POLE4
Variant:p.D100N

POLE4

209 papers

RefSeq Summary

POLE4 is a histone-fold protein that interacts with other histone-fold proteins to bind DNA in a sequence-independent manner. These histone-fold protein dimers combine within larger enzymatic complexe...

Pfam Domains

CBFD_NFYB_HMFaa 39–103UCSCHistone-like transcription factor (CBF/NF-Y) and archaeal histone

Gene Aliases

HGNC Name

DNA polymerase epsilon 4, accessory subunit

HGNC Alias Symbol

p12

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_019896.4
p.D100N
c.298G>A
Surrounding Variants
1 paper
NM_019896.4
p.D98V
c.293A>T
1 paper
NM_019896.4
p.R96_R97insTG
c.286_290ins6
2 papers
NM_019896.4
p.K92E
c.274A>G
1 paper
NM_019896.4
p.G89_K90del2
c.265_269del6
1 paper
NM_019896.4
p.Q88*
c.262C>T
1 paper
NM_019896.4
p.C85F
c.254G>T
1 paper
NM_019896.4
p.Y83F
c.248A>T
1 paper
NM_019896.4
p.Y83insFs
c.247_248insC
1 paper
NM_019896.4
p.A82G
c.245C>G
1 paper
NM_019896.4
p.A82insFs
c.244_245insG
1 paper
NM_019896.4
p.T77_I78insT
c.229_233ins3
1 paper
NM_019896.4
p.E76insFs
c.226_227ins16
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