Varaico: Literature-Extracted Genetic Variants

POLL

108 papers

RefSeq Summary

This gene encodes a DNA polymerase. DNA polymerases catalyze DNA-template-directed extension of the 3'-end of a DNA strand. This particular polymerase, which is a member of the X family of DNA polymer...

Pfam Domains

HHH_8aa 251–322UCSCHelix-hairpin-helix domain

DNA_pol_lambd_faa 336–384UCSCFingers domain of DNA polymerase lambda

DNA_pol_B_palmaa 386–496UCSCDNA polymerase beta palm

DNA_pol_B_thumbaa 502–574UCSCDNA polymerase beta thumb

Gene Aliases

HGNC Name

DNA polymerase lambda

HGNC Previous Names

polymerase (DNA directed), lambda; polymerase (DNA) lambda

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001174084.2

p.R573W

c.1717C>T

Surrounding Variants

1 paper

NM_001174084.2

p.R549*

c.1645C>T

1 paper

NM_001174084.2

p.R538W

c.1612C>T

1 paper

NM_001174084.2

p.R517Q

c.1550G>A

1 paper

NM_001174084.2

p.R514L

c.1541G>T

1 paper

NM_001174084.2

p.A500T

c.1498G>A

1 paper

NM_001174084.2

p.E498K

c.1492G>A

1 paper

NM_001174084.2

p.R487L

c.1460G>T

1 paper

NM_001174084.2

p.P480S

c.1438C>T

1 paper

NM_001174084.2

p.Q471L

c.1412A>T

1 paper

NM_001174084.2

p.G455W

c.1363G>T

1 paper

NM_001174084.2

p.R452Q

c.1355G>A

1 paper

NM_001174084.2

p.R446L

c.1337G>T