Varaico: Literature-Extracted Genetic Variants

POLL

108 papers

RefSeq Summary

This gene encodes a DNA polymerase. DNA polymerases catalyze DNA-template-directed extension of the 3'-end of a DNA strand. This particular polymerase, which is a member of the X family of DNA polymer...

Pfam Domains

HHH_8aa 251–322UCSCHelix-hairpin-helix domain

DNA_pol_lambd_faa 336–384UCSCFingers domain of DNA polymerase lambda

DNA_pol_B_palmaa 386–496UCSCDNA polymerase beta palm

DNA_pol_B_thumbaa 502–574UCSCDNA polymerase beta thumb

Gene Aliases

HGNC Name

DNA polymerase lambda

HGNC Previous Names

polymerase (DNA directed), lambda; polymerase (DNA) lambda

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_001174084.2

p.G376S

c.1126G>A

Surrounding Variants

1 paper

NM_001174084.2

p.R364H

c.1091G>A

1 paper

NM_001174084.2

p.D362N

c.1084G>A

1 paper

NM_001174084.2

p.R358Q

c.1073G>A

1 paper

NM_001174084.2

p.R358*

c.1072C>T

2 papers

NM_001174084.2

p.G356S

c.1066G>A

1 paper

NM_001174084.2

p.Y353C

c.1058A>G

3 papers

NM_001174084.2

p.A349V

c.1046C>T

2 papers

NM_001174084.2

p.L337L

c.1011C>T

1 paper

NM_001174084.2

p.L335F

c.1005G>T

1 paper

NM_001174084.2

p.L335F

c.1005G>C

1 paper

NM_001174084.2

p.V334A

c.1001T>C

1 paper

NM_001174084.2

p.E330A

c.989A>C