Varaico: Literature-Extracted Genetic Variants

POLL

108 papers

RefSeq Summary

This gene encodes a DNA polymerase. DNA polymerases catalyze DNA-template-directed extension of the 3'-end of a DNA strand. This particular polymerase, which is a member of the X family of DNA polymer...

Pfam Domains

HHH_8aa 251–322UCSCHelix-hairpin-helix domain

DNA_pol_lambd_faa 336–384UCSCFingers domain of DNA polymerase lambda

DNA_pol_B_palmaa 386–496UCSCDNA polymerase beta palm

DNA_pol_B_thumbaa 502–574UCSCDNA polymerase beta thumb

Gene Aliases

HGNC Name

DNA polymerase lambda

HGNC Previous Names

polymerase (DNA directed), lambda; polymerase (DNA) lambda

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001174084.2

p.A242G

c.725C>G

Surrounding Variants

1 paper

NM_001174084.2

p.A249V

c.746C>T

1 paper

NM_001174084.2

p.N251S

c.752A>G

1 paper

NM_001174084.2

p.E261G

c.782A>G

6 papers

NM_001174084.2

p.T221P

c.661A>C

1 paper

NM_001174084.2

p.A266G

c.797C>G

1 paper

NM_001174084.2

p.A276S

c.826G>T

1 paper

NM_001174084.2

p.T204A

c.610A>G

1 paper

NM_001174084.2

p.K273_N284del0

c.819_851del33

3 papers

NM_001174084.2

p.S288C

c.862A>T

1 paper

NM_001174084.2

p.S295L

c.884C>T

1 paper

NM_001174084.2

p.T188A

c.562A>G

1 paper

NM_001174084.2

p.P175S

c.523C>T