Varaico: Literature-Extracted Genetic Variants

POLL

108 papers

RefSeq Summary

This gene encodes a DNA polymerase. DNA polymerases catalyze DNA-template-directed extension of the 3'-end of a DNA strand. This particular polymerase, which is a member of the X family of DNA polymer...

Pfam Domains

HHH_8aa 251–322UCSCHelix-hairpin-helix domain

DNA_pol_lambd_faa 336–384UCSCFingers domain of DNA polymerase lambda

DNA_pol_B_palmaa 386–496UCSCDNA polymerase beta palm

DNA_pol_B_thumbaa 502–574UCSCDNA polymerase beta thumb

Gene Aliases

HGNC Name

DNA polymerase lambda

HGNC Previous Names

polymerase (DNA directed), lambda; polymerase (DNA) lambda

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001174084.2

p.D2fs

c.4_5fs

Surrounding Variants

1 paper

NM_001174084.2

p.D2E

c.6T>G

1 paper

NM_001174084.2

p.D2E

c.6T>A

1 paper

NM_001174084.2

p.M1insFs

c.1_2ins7

1 paper

NM_001174084.2

p.M1_D2ins7

c.1_5ins21

1 paper

NM_001174084.2

p.G5R

c.13G>C

1 paper

NM_001174084.2

p.F10L

c.28T>C

1 paper

NM_001174084.2

p.F10L

c.30T>G

1 paper

NM_001174084.2

p.F10L

c.30T>A

1 paper

NM_001174084.2

p.P11insFs

c.31dupC

1 paper

NM_001174084.2

p.K8_Q14delFs

c.22_40del19

1 paper

NM_001174084.2

p.I16_H17del1

c.48_50delTGA

1 paper

NM_001174084.2

p.E33K

c.97G>A