Varaico: Literature-Extracted Genetic Variants

POLR2C

40 papers

RefSeq Summary

This gene encodes the third largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a cysteine rich region and ...

Pfam Domains

RNA_pol_Laa 20–256UCSCRNA polymerase Rpb3/Rpb11 dimerisation domain

RNA_pol_A_bacaa 50–182UCSCRNA polymerase Rpb3/RpoA insert domain

Gene Aliases

HGNC Name

RNA polymerase II subunit C

HGNC Alias Symbol

RPB3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_032940.3

p.F229S

c.686T>C

Surrounding Variants

1 paper

NM_032940.3

p.R240C

c.718C>T

1 paper

NM_032940.3

p.E242K

c.724G>A

1 paper

NM_032940.3

p.K255K

c.765A>G

1 paper

NM_032940.3

p.S257R

c.769A>C

1 paper

NM_032940.3

p.S257R

c.771T>A

1 paper

NM_032940.3

p.S257R

c.771T>G

1 paper

NM_032940.3

p.D258G

c.773A>G

1 paper

NM_032940.3

p.L259L

c.775T>C

1 paper

NM_032940.3

p.G224S

c.670G>A

1 paper

NM_032940.3

p.K205N

c.615G>C

1 paper

NM_032940.3

p.F184L

c.550T>C

1 paper

NM_032940.3

p.V182A

c.545T>C