Varaico: Literature-Extracted Genetic Variants

PPARA

1,249 papers

RefSeq Summary

Peroxisome proliferators include hypolipidemic drugs, herbicides, leukotriene antagonists, and plasticizers; this term arises because they induce an increase in the size and number of peroxisomes. Per...

Pfam Domains

zf-C4aa 100–168UCSCDouble treble clef zinc finger, C4 type

Hormone_recepaa 262–449UCSCLigand-binding domain of nuclear hormone receptor

Gene Aliases

HGNC Name

peroxisome proliferator activated receptor alpha

HGNC Previous Symbol

PPAR

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_005036.6

p.L134delFs

c.400delC

Surrounding Variants

1 paper

NM_005036.6

p.K133N

c.399G>C

1 paper

NM_005036.6

p.K133N

c.399G>T

1 paper

NM_005036.6

p.K133M

c.398A>T

2 papers

NM_005036.6

p.K133E

c.397A>G

1 paper

NM_005036.6

p.L134P

c.401T>C

1 paper

NM_005036.6

p.L132I

c.394C>A

2 papers

NM_005036.6

p.L132V

c.394C>G

1 paper

NM_005036.6

p.V135V

c.405G>C

5 papers

NM_005036.6

p.R131Q

c.392G>A

1 paper

NM_005036.6

p.R131L

c.392G>T

1 paper

NM_005036.6

p.Y136F

c.407A>T

1 paper

NM_005036.6

p.I130V

c.388A>G