Varaico: Literature-Extracted Genetic Variants

PPARA

1,249 papers

RefSeq Summary

Peroxisome proliferators include hypolipidemic drugs, herbicides, leukotriene antagonists, and plasticizers; this term arises because they induce an increase in the size and number of peroxisomes. Per...

Pfam Domains

zf-C4aa 100–168UCSCDouble treble clef zinc finger, C4 type

Hormone_recepaa 262–449UCSCLigand-binding domain of nuclear hormone receptor

Gene Aliases

HGNC Name

peroxisome proliferator activated receptor alpha

HGNC Previous Symbol

PPAR

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

4 papers

NM_005036.6

p.L344P

c.1031T>C

Surrounding Variants

1 paper

NM_005036.6

p.R341H

c.1022G>A

1 paper

NM_005036.6

p.R341C

c.1021C>T

1 paper

NM_005036.6

p.I339K

c.1016T>A

1 paper

NM_005036.6

p.G335A

c.1004G>C

1 paper

NM_005036.6

p.I354V

c.1060A>G

1 paper

NM_005036.6

p.A333G

c.998C>G

2 papers

NM_005036.6

p.A333V

c.998C>T

1 paper

NM_005036.6

p.M355I

c.1065G>A

1 paper

NM_005036.6

p.M355I

c.1065G>C

1 paper

NM_005036.6

p.A333fs

c.997_998fs

1 paper

NM_005036.6

p.M355I

c.1065G>T

1 paper

NM_005036.6

p.E356K

c.1066G>A