Varaico: Literature-Extracted Genetic Variants

PPARA

1,249 papers

RefSeq Summary

Peroxisome proliferators include hypolipidemic drugs, herbicides, leukotriene antagonists, and plasticizers; this term arises because they induce an increase in the size and number of peroxisomes. Per...

Pfam Domains

zf-C4aa 100–168UCSCDouble treble clef zinc finger, C4 type

Hormone_recepaa 262–449UCSCLigand-binding domain of nuclear hormone receptor

Gene Aliases

HGNC Name

peroxisome proliferator activated receptor alpha

HGNC Previous Symbol

PPAR

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_005036.6

p.D374Y

c.1120G>T

Surrounding Variants

5 papers

NM_005036.6

p.L377L

c.1131T>C

2 papers

NM_005036.6

p.L370R

c.1109T>G

1 paper

NM_005036.6

p.A367V

c.1100C>T

1 paper

NM_005036.6

p.A367delFs

c.1100delC

1 paper

NM_005036.6

p.C385Y

c.1154G>A

1 paper

NM_005036.6

p.A362V

c.1085C>T

1 paper

NM_005036.6

p.E356K

c.1066G>A

1 paper

NM_005036.6

p.M355I

c.1065G>A

1 paper

NM_005036.6

p.M355I

c.1065G>C

1 paper

NM_005036.6

p.M355I

c.1065G>T

1 paper

NM_005036.6

p.I354V

c.1060A>G

4 papers

NM_005036.6

p.L344P

c.1031T>C