Varaico: Literature-Extracted Genetic Variants

PPARG

903 papers

RefSeq Summary

This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regu...

Pfam Domains

PPARgamma_Naa 1–78UCSCPPAR gamma N-terminal region

zf-C4aa 107–175UCSCDouble treble clef zinc finger, C4 type

zf-C4aa 137–205UCSCDouble treble clef zinc finger, C4 type

Hormone_recepaa 269–456UCSCLigand-binding domain of nuclear hormone receptor

Gene Aliases

HGNC Name

peroxisome proliferator activated receptor gamma

HGNC Alias Symbols

PPARG1; PPARG2; NR1C3; PPARgamma

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_138711.6

p.V60I

c.178G>A

Surrounding Variants

1 paper

NM_138711.6

p.V59_V60ins1

c.177_178insCTC

1 paper

NM_138711.6

p.V59_V60insFs

c.177_178ins17

1 paper

NM_138711.6

p.V59G

c.176T>G

1 paper

NM_138711.6

p.A61P

c.181G>C

1 paper

NM_138711.6

p.P58_V59insFs

c.174_175ins8

1 paper

NM_138711.6

p.P58A

c.172C>G

1 paper

NM_015869.5

p.D92N

c.274G>A

1 paper

NM_138711.6

p.Y63C

c.188A>G

1 paper

NM_138711.6

p.Y63F

c.188A>T

1 paper

NM_138711.6

p.T56_D62ins2

c.168_185dup18

1 paper

NM_138711.6

p.K64*

c.190A>T

1 paper

NM_138711.6

p.K64R

c.191A>G