Varaico: Literature-Extracted Genetic Variants

PPARG

903 papers

RefSeq Summary

This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regu...

Pfam Domains

PPARgamma_Naa 1–78UCSCPPAR gamma N-terminal region

zf-C4aa 107–175UCSCDouble treble clef zinc finger, C4 type

zf-C4aa 137–205UCSCDouble treble clef zinc finger, C4 type

Hormone_recepaa 269–456UCSCLigand-binding domain of nuclear hormone receptor

Gene Aliases

HGNC Name

peroxisome proliferator activated receptor gamma

HGNC Alias Symbols

PPARG1; PPARG2; NR1C3; PPARgamma

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_138711.6

p.Y93insFs

c.279dupC

Surrounding Variants

1 paper

NM_138711.6

p.Y93F

c.278A>T

1 paper

NM_015869.5

p.Y123*

c.369C>G

2 papers

NM_138711.6

p.K95R

c.284A>G

1 paper

NM_138711.6

p.Q91K

c.271C>A

1 paper

NM_138711.6

p.P96L

c.287C>T

1 paper

NM_138711.6

p.K89R

c.266A>G

1 paper

NM_138711.6

p.E88G

c.263A>G

1 paper

NM_138711.6

p.E98D

c.294A>C

1 paper

NM_138711.6

p.E98D

c.294A>T

2 papers

NM_138711.6

p.S87T

c.259T>A

1 paper

NM_138711.6

p.P100insFs

c.298_299ins4

1 paper

NM_138711.6

p.Y86_S87insFs

c.258_259ins4