Varaico: Literature-Extracted Genetic Variants

PPARG

903 papers

RefSeq Summary

This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regu...

Pfam Domains

PPARgamma_Naa 1–78UCSCPPAR gamma N-terminal region

zf-C4aa 107–175UCSCDouble treble clef zinc finger, C4 type

zf-C4aa 137–205UCSCDouble treble clef zinc finger, C4 type

Hormone_recepaa 269–456UCSCLigand-binding domain of nuclear hormone receptor

Gene Aliases

HGNC Name

peroxisome proliferator activated receptor gamma

HGNC Alias Symbols

PPARG1; PPARG2; NR1C3; PPARgamma

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_015869.5

p.E157D

c.471A>C

Surrounding Variants

2 papers

NM_015869.5

p.E157D

c.471A>T

1 paper

NM_138711.6

p.E127A

c.380A>C

1 paper

NM_138711.6

p.E127G

c.380A>G

1 paper

NM_138711.6

p.C126insFs

c.377_378insT

1 paper

NM_138711.6

p.C129S

c.385T>A

3 papers

NM_015869.5

p.C159Y

c.476G>A

1 paper

NM_138711.6

p.C129*

c.387C>A

1 paper

NM_138711.6

p.K130E

c.388A>G

2 papers

NM_138711.6

p.K130_G131Splc

c.390+1G>A

2 papers

NM_138711.6

p.K130_G131Splc

c.390+7A>T

8 papers

NM_015869.5

p.Y151C

c.452A>G

NM_138711.6

p.Y121C

c.362A>G

1 paper

NM_015869.5

p.H150L

c.449A>T