Varaico: Literature-Extracted Genetic Variants

PPARG

903 papers

RefSeq Summary

This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regu...

Pfam Domains

PPARgamma_Naa 1–78UCSCPPAR gamma N-terminal region

zf-C4aa 107–175UCSCDouble treble clef zinc finger, C4 type

zf-C4aa 137–205UCSCDouble treble clef zinc finger, C4 type

Hormone_recepaa 269–456UCSCLigand-binding domain of nuclear hormone receptor

Gene Aliases

HGNC Name

peroxisome proliferator activated receptor gamma

HGNC Alias Symbols

PPARG1; PPARG2; NR1C3; PPARgamma

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_138711.6

p.F133L

c.397T>C

Surrounding Variants

1 paper

NM_138711.6

p.R134delFs

c.400delC

5 papers

NM_015869.5

p.R164W

c.490C>T

1 paper

NM_015869.5

p.G161D

c.482G>A

4 papers

NM_015869.5

p.G161V

c.482G>T

2 papers

NM_138711.6

p.R134R

c.402G>T

1 paper

NM_138711.6

p.R135G

c.403A>G

1 paper

NM_138711.6

p.G131S

c.391G>A

1 paper

NM_138711.6

p.R135K

c.404G>A

4 papers

NM_015869.5

p.R165T

c.494G>C

1 paper

NM_138711.6

p.K130_G131Splc

c.391-2A>G

2 papers

NM_138711.6

p.K130_G131Splc

c.391-3C>T

1 paper

NM_138711.6

p.I137N

c.410T>A