Varaico: Literature-Extracted Genetic Variants

PPARG

903 papers

RefSeq Summary

This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regu...

Pfam Domains

PPARgamma_Naa 1–78UCSCPPAR gamma N-terminal region

zf-C4aa 107–175UCSCDouble treble clef zinc finger, C4 type

zf-C4aa 137–205UCSCDouble treble clef zinc finger, C4 type

Hormone_recepaa 269–456UCSCLigand-binding domain of nuclear hormone receptor

Gene Aliases

HGNC Name

peroxisome proliferator activated receptor gamma

HGNC Alias Symbols

PPARG1; PPARG2; NR1C3; PPARgamma

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_138711.6

p.K140insFs

c.418dupA

Surrounding Variants

2 papers

NM_138711.6

p.L139L

c.417G>A

1 paper

NM_138711.6

p.K140delFs

c.419delA

1 paper

NM_138711.6

p.K140K

c.420G>A

1 paper

NM_138711.6

p.K140N

c.420G>C

1 paper

NM_138711.6

p.L141I

c.421C>A

1 paper

NM_015869.5

p.R168K

c.503G>A

1 paper

NM_138711.6

p.I137N

c.410T>A

1 paper

NM_015869.5

p.Y173C

c.518A>G

1 paper

NM_138711.6

p.Y143Y

c.429T>C

2 papers

NM_138711.6

p.D144N

c.430G>A

1 paper

NM_138711.6

p.R135K

c.404G>A

4 papers

NM_015869.5

p.R165T

c.494G>C