Varaico: Literature-Extracted Genetic Variants

PPARG

903 papers

RefSeq Summary

This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regu...

Pfam Domains

PPARgamma_Naa 1–78UCSCPPAR gamma N-terminal region

zf-C4aa 107–175UCSCDouble treble clef zinc finger, C4 type

zf-C4aa 137–205UCSCDouble treble clef zinc finger, C4 type

Hormone_recepaa 269–456UCSCLigand-binding domain of nuclear hormone receptor

Gene Aliases

HGNC Name

peroxisome proliferator activated receptor gamma

HGNC Alias Symbols

PPARG1; PPARG2; NR1C3; PPARgamma

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_015869.5

p.C190S

c.568T>A

Surrounding Variants

2 papers

NM_015869.5

p.C190S

c.569G>C

1 paper

NM_138711.6

p.C160*

c.480T>A

2 papers

NM_015869.5

p.C190W

c.570T>G

1 paper

NM_015869.5

p.Q191*

c.571C>T

1 paper

NM_138711.6

p.N158K

c.474T>A

2 papers

NM_015869.5

p.N188H

c.562A>C

1 paper

NM_138711.6

p.N158D

c.472A>G

1 paper

NM_138711.6

p.Y162N

c.484T>A

1 paper

NM_138711.6

p.N158delFs

c.472delA

1 paper

NM_138711.6

p.C163Y

c.488G>A

1 paper

NM_138711.6

p.S156R

c.468T>A

2 papers

NM_138711.6

p.C163C

c.489T>C