Varaico: Literature-Extracted Genetic Variants

PPARG

903 papers

RefSeq Summary

This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regu...

Pfam Domains

PPARgamma_Naa 1–78UCSCPPAR gamma N-terminal region

zf-C4aa 107–175UCSCDouble treble clef zinc finger, C4 type

zf-C4aa 137–205UCSCDouble treble clef zinc finger, C4 type

Hormone_recepaa 269–456UCSCLigand-binding domain of nuclear hormone receptor

Gene Aliases

HGNC Name

peroxisome proliferator activated receptor gamma

HGNC Alias Symbols

PPARG1; PPARG2; NR1C3; PPARgamma

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_138711.6

p.K167E

c.499A>G

Surrounding Variants

1 paper

NM_138711.6

p.K167I

c.500A>T

1 paper

NM_138711.6

p.Q166*

c.496C>T

1 paper

NM_138711.6

p.F165F

c.495T>C

1 paper

NM_138711.6

p.F165delins

c.493_494delinsGC

5 papers

NM_138711.6

p.R164Q

c.491G>A

NM_015869.5

p.R194Q

c.581G>A

11 papers

NM_015869.5

p.R194W

c.580C>T

NM_138711.6

p.R164W

c.490C>T

2 papers

NM_138711.6

p.A170V

c.509C>T

2 papers

NM_138711.6

p.C163C

c.489T>C

1 paper

NM_138711.6

p.C163Y

c.488G>A

1 paper

NM_138711.6

p.G172R

c.514G>A

1 paper

NM_138711.6

p.Y162N

c.484T>A

1 paper

NM_138711.6

p.G172E

c.515G>A