Varaico: Literature-Extracted Genetic Variants

PPARG

903 papers

RefSeq Summary

This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regu...

Pfam Domains

PPARgamma_Naa 1–78UCSCPPAR gamma N-terminal region

zf-C4aa 107–175UCSCDouble treble clef zinc finger, C4 type

zf-C4aa 137–205UCSCDouble treble clef zinc finger, C4 type

Hormone_recepaa 269–456UCSCLigand-binding domain of nuclear hormone receptor

Gene Aliases

HGNC Name

peroxisome proliferator activated receptor gamma

HGNC Alias Symbols

PPARG1; PPARG2; NR1C3; PPARgamma

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_138711.6

p.E187E

c.561G>A

Surrounding Variants

1 paper

NM_138711.6

p.E187D

c.561G>C

1 paper

NM_138711.6

p.E187D

c.561G>T

1 paper

NM_138711.6

p.E187A

c.560A>C

2 papers

NM_138711.6

p.E187G

c.560A>G

1 paper

NM_138711.6

p.E187V

c.560A>T

1 paper

NM_138711.6

p.K188M

c.563A>T

1 paper

NM_015869.5

p.E217K

c.649G>A

1 paper

NM_138711.6

p.A186D

c.557C>A

1 paper

NM_138711.6

p.A186G

c.557C>G

1 paper

NM_138711.6

p.A186V

c.557C>T

1 paper

NM_138711.6

p.E189K

c.565G>A

1 paper

NM_138711.6

p.E189Q

c.565G>C