Varaico: Literature-Extracted Genetic Variants

PPARG

903 papers

RefSeq Summary

This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regu...

Pfam Domains

PPARgamma_Naa 1–78UCSCPPAR gamma N-terminal region

zf-C4aa 107–175UCSCDouble treble clef zinc finger, C4 type

zf-C4aa 137–205UCSCDouble treble clef zinc finger, C4 type

Hormone_recepaa 269–456UCSCLigand-binding domain of nuclear hormone receptor

Gene Aliases

HGNC Name

peroxisome proliferator activated receptor gamma

HGNC Alias Symbols

PPARG1; PPARG2; NR1C3; PPARgamma

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_138711.6

p.D218delFs

c.652delG

Surrounding Variants

1 paper

NM_138711.6

p.D218G

c.653A>G

1 paper

NM_138711.6

p.D218E

c.654C>G

1 paper

NM_015869.5

p.S249L

c.746C>T

2 papers

NM_138711.6

p.Y220C

c.659A>G

1 paper

NM_138711.6

p.A213_K214insT

c.637_641ins3

1 paper

NM_138711.6

p.S223_L235Fs

c.667_705delinsCTGCGFs

3 papers

NM_138711.6

p.L212L

c.634C>T

1 paper

NM_138711.6

p.S223F

c.668C>T

1 paper

NM_138711.6

p.L212insFs

c.634dupC

1 paper

NM_138711.6

p.R210_H215del0

c.630_644del15

2 papers

NM_015869.5

p.R240W

c.718C>T

1 paper

NM_138711.6

p.A211delFs

c.631delG