Varaico: Literature-Extracted Genetic Variants

PPARG

903 papers

RefSeq Summary

This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regu...

Pfam Domains

PPARgamma_Naa 1–78UCSCPPAR gamma N-terminal region

zf-C4aa 107–175UCSCDouble treble clef zinc finger, C4 type

zf-C4aa 137–205UCSCDouble treble clef zinc finger, C4 type

Hormone_recepaa 269–456UCSCLigand-binding domain of nuclear hormone receptor

Gene Aliases

HGNC Name

peroxisome proliferator activated receptor gamma

HGNC Alias Symbols

PPARG1; PPARG2; NR1C3; PPARgamma

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

27 papers

NM_138711.6

p.T227T

c.681C>G

Surrounding Variants

2 papers

NM_138711.6

p.T227T

c.681C>T

1 paper

NM_015869.5

p.A259T

c.775G>A

3 papers

NM_138711.6

p.A229S

c.685G>T

1 paper

NM_138711.6

p.L226L

c.676C>T

1 paper

NM_015869.5

p.A261P

c.781G>C

1 paper

NM_015869.5

p.A261E

c.782C>A

1 paper

NM_138711.6

p.A233insFs

c.697dupG

1 paper

NM_015869.5

p.R262G

c.784A>G

1 paper

NM_138711.6

p.S223F

c.668C>T

1 paper

NM_138711.6

p.S223_L235Fs

c.667_705delinsCTGCGFs

1 paper

NM_138711.6

p.A233fs

c.697_698fs

1 paper

NM_138711.6

p.A233E

c.698C>A