Varaico: Literature-Extracted Genetic Variants

PPARG

903 papers

RefSeq Summary

This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regu...

Pfam Domains

PPARgamma_Naa 1–78UCSCPPAR gamma N-terminal region

zf-C4aa 107–175UCSCDouble treble clef zinc finger, C4 type

zf-C4aa 137–205UCSCDouble treble clef zinc finger, C4 type

Hormone_recepaa 269–456UCSCLigand-binding domain of nuclear hormone receptor

Gene Aliases

HGNC Name

peroxisome proliferator activated receptor gamma

HGNC Alias Symbols

PPARG1; PPARG2; NR1C3; PPARgamma

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_138711.6

p.G397D

c.1190G>A

Surrounding Variants

1 paper

NM_138711.6

p.P396P

c.1188A>C

1 paper

NM_015869.5

p.P426L

c.1277C>T

1 paper

NM_015869.5

p.P426_L429del0

c.1278_1286del9

1 paper

NM_015869.5

p.R425H

c.1274G>A

9 papers

NM_015869.5

p.R425C

c.1273C>T

NM_138711.6

p.R395C

c.1183C>T

1 paper

NM_138711.6

p.V401M

c.1201G>A

1 paper

NM_138711.6

p.K402K

c.1206G>A

2 papers

NM_138711.6

p.K402N

c.1206G>C

2 papers

NM_138711.6

p.K402N

c.1206G>T

1 paper

NM_138711.6

p.P403delFs

c.1209delC

1 paper

NM_138711.6

p.P403S

c.1207C>T

1 paper

NM_015869.5

p.I434T

c.1301T>C