Varaico: Literature-Extracted Genetic Variants

PPARG

903 papers

RefSeq Summary

This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regu...

Pfam Domains

PPARgamma_Naa 1–78UCSCPPAR gamma N-terminal region

zf-C4aa 107–175UCSCDouble treble clef zinc finger, C4 type

zf-C4aa 137–205UCSCDouble treble clef zinc finger, C4 type

Hormone_recepaa 269–456UCSCLigand-binding domain of nuclear hormone receptor

Gene Aliases

HGNC Name

peroxisome proliferator activated receptor gamma

HGNC Alias Symbols

PPARG1; PPARG2; NR1C3; PPARgamma

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

7 papers

NM_138711.6

p.L451P

c.1352T>C

Surrounding Variants

1 paper

NM_138711.6

p.L451V

c.1351C>G

2 papers

NM_138711.6

p.Q449L

c.1346A>T

1 paper

NM_138711.6

p.Q449*

c.1345C>T

1 paper

NM_138711.6

p.V453V

c.1359G>A

1 paper

NM_138711.6

p.I454delFs

c.1361delT

1 paper

NM_015869.5

p.V478G

c.1433T>G

9 papers

NM_015869.5

p.H477H

c.1431C>T

NM_138711.6

p.H447H

c.1341C>T

1 paper

NM_138711.6

p.K455R

c.1364A>G

1 paper

NM_015869.5

p.H477L

c.1430A>T

2 papers

NM_138711.6

p.T445T

c.1335G>A

1 paper

NM_138711.6

p.E446_K455delFs

c.1337_1365del29

3 papers

NM_015869.5

p.T475M

c.1424C>T