Varaico: Literature-Extracted Genetic Variants

PPM1B

59 papers

RefSeq Summary

The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphat...

Pfam Domains

PP2Caa 22–288UCSCProtein phosphatase 2C

PP2C_Caa 289–368UCSCProtein serine/threonine phosphatase 2C, C-terminal domain

Gene Aliases

HGNC Name

protein phosphatase, Mg2+/Mn2+ dependent 1B

HGNC Alias Symbols

PPC2BETAX; PP2CB; PP2CBETA

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002706.6

p.R33K

c.98G>A

Surrounding Variants

1 paper

NM_002706.6

p.M29T

c.86T>C

1 paper

NM_002706.6

p.R23H

c.68G>A

1 paper

NM_002706.6

p.G21S

c.61G>A

1 paper

NM_002706.6

p.P47R

c.140C>G

1 paper

NM_002706.6

p.A18T

c.52G>A

1 paper

NM_002706.6

p.D60A

c.179A>C

1 paper

NM_002706.6

p.D6N

c.16G>A

1 paper

NM_002706.6

p.G61A

c.182G>C

1 paper

NM_002706.6

p.G2A

c.5G>C

1 paper

NM_002706.6

p.S65A

c.193T>G

1 paper

NM_002706.6

p.R66*

c.196C>T

2 papers

NM_002706.6

p.E83K

c.247G>A