Varaico: Literature-Extracted Genetic Variants

Gene:PPME1
Variant:p.S127A

PPME1

23 papers

RefSeq Summary

This gene encodes a protein phosphatase methylesterase localized to the nucleus. The encoded protein acts on the protein phosphatase-2A catalytic subunit and supports the ERK pathway through dephospho...

Pfam Domains

Abhydrolase_6aa 79–362UCSCAlpha/beta hydrolase family

Gene Aliases

HGNC Name

protein phosphatase methylesterase 1

HGNC Alias Symbols

PME-1; ABDH19

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_016147.3
p.S127A
c.379T>G
Surrounding Variants
1 paper
NM_016147.3
p.K133Splc
c.399-1G>A
1 paper
NM_016147.3
p.I212V
c.634A>G
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."