Varaico: Literature-Extracted Genetic Variants

PPP1CB

159 papers

RefSeq Summary

The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of...

Pfam Domains

STPPase_Naa 8–55UCSCSerine-threonine protein phosphatase N-terminal domain

Metallophosaa 56–251UCSCCalcineurin-like phosphoesterase

Gene Aliases

HGNC Name

protein phosphatase 1 catalytic subunit beta

HGNC Alias Symbols

PP1B; PP-1B; PP1beta; PP1c; MP; PPP1beta

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002709.3

p.R35R

c.105A>G

Surrounding Variants

1 paper

NM_002709.3

p.R35P

c.104G>C

1 paper

NM_002709.3

p.L37_I39delFs

c.110_116del7

1 paper

NM_002709.3

p.C38C

c.114T>C

1 paper

NM_002709.3

p.A32T

c.94G>A

1 paper

NM_002709.3

p.I44T

c.131T>C

37 papers

NM_002709.3

p.P49R

c.146C>G

1 paper

NM_002709.3

p.R19R

c.57A>G

1 paper

NM_002709.3

p.R19Q

c.56G>A

1 paper

NM_002709.3

p.R19*

c.55C>T

1 paper

NM_002709.3

p.E53K

c.157G>A

1 paper

NM_002709.3

p.E53A

c.158A>C

1 paper

NM_002709.3

p.E55A

c.164A>C