Varaico: Literature-Extracted Genetic Variants

PPP1CB

159 papers

RefSeq Summary

The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of...

Pfam Domains

STPPase_Naa 8–55UCSCSerine-threonine protein phosphatase N-terminal domain

Metallophosaa 56–251UCSCCalcineurin-like phosphoesterase

Gene Aliases

HGNC Name

protein phosphatase 1 catalytic subunit beta

HGNC Alias Symbols

PP1B; PP-1B; PP1beta; PP1c; MP; PPP1beta

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

6 papers

NM_002709.3

p.E183V

c.548A>T

Surrounding Variants

11 papers

NM_002709.3

p.E183A

c.548A>C

2 papers

NM_002709.3

p.M182K

c.545T>A

1 paper

NM_002709.3

p.S181C

c.542C>G

1 paper

NM_002709.3

p.S181_M182insT

c.541_545ins3

1 paper

NM_002709.3

p.R190T

c.569G>C

1 paper

NM_002709.3

p.G198S

c.592G>A

1 paper

NM_002709.3

p.G173_G174delins

c.519_520delinsAT

1 paper

NM_002709.3

p.I168N

c.503T>A

1 paper

NM_002709.3

p.E166A

c.497A>C

1 paper

NM_002709.3

p.D165A

c.494A>C

1 paper

NM_002709.3

p.A161T

c.481G>A

1 paper

NM_002709.3

p.P159T

c.475C>A