Varaico: Literature-Extracted Genetic Variants

PPP1CB

159 papers

RefSeq Summary

The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of...

Pfam Domains

STPPase_Naa 8–55UCSCSerine-threonine protein phosphatase N-terminal domain

Metallophosaa 56–251UCSCCalcineurin-like phosphoesterase

Gene Aliases

HGNC Name

protein phosphatase 1 catalytic subunit beta

HGNC Alias Symbols

PP1B; PP-1B; PP1beta; PP1c; MP; PPP1beta

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_002709.3

p.S223fs

c.667_668fs

Surrounding Variants

1 paper

NM_002709.3

p.S223Y

c.668C>A

3 papers

NM_002709.3

p.S223insFs

c.667dupT

1 paper

NM_002709.3

p.R220C

c.658C>T

1 paper

NM_002709.3

p.E217del1

c.649_650delGAA

1 paper

NM_002709.3

p.S232R

c.696T>A

1 paper

NM_002709.3

p.K233E

c.697A>G

1 paper

NM_002709.3

p.D211N

c.631G>A

1 paper

NM_002709.3

p.N236H

c.706A>C

1 paper

NM_002709.3

p.I243M

c.729T>G

1 paper

NM_002709.3

p.Q248E

c.742C>G

1 paper

NM_002709.3

p.G198S

c.592G>A

1 paper

NM_002709.3

p.R190T

c.569G>C