Varaico: Literature-Extracted Genetic Variants

PPP1CB

159 papers

RefSeq Summary

The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of...

Pfam Domains

STPPase_Naa 8–55UCSCSerine-threonine protein phosphatase N-terminal domain

Metallophosaa 56–251UCSCCalcineurin-like phosphoesterase

Gene Aliases

HGNC Name

protein phosphatase 1 catalytic subunit beta

HGNC Alias Symbols

PP1B; PP-1B; PP1beta; PP1c; MP; PPP1beta

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002709.3

p.F257_A258insFs

c.771_772insT

Surrounding Variants

1 paper

NM_002709.3

p.G253E

c.758G>A

1 paper

NM_002709.3

p.A258fs

c.772_773fs

5 papers

NM_002709.3

p.D252Y

c.754G>T

1 paper

NM_002709.3

p.R260P

c.779G>C

1 paper

NM_002709.3

p.Q261E

c.781C>G

1 paper

NM_002709.3

p.V250M

c.748G>A

1 paper

NM_002709.3

p.V263G

c.788T>G

1 paper

NM_002709.3

p.S267*

c.800C>A

1 paper

NM_002709.3

p.S267*

c.800C>G

1 paper

NM_002709.3

p.A268T

c.802G>A

1 paper

NM_002709.3

p.P269L

c.806C>T

7 papers

NM_002709.3

p.E274K

c.820G>A