Varaico: Literature-Extracted Genetic Variants

Gene:PPP1R13L
Variant:p.K23*

PPP1R13L

90 papers

RefSeq Summary

IASPP is one of the most evolutionarily conserved inhibitors of p53 (TP53; MIM 191170), whereas ASPP1 (MIM 606455) and ASPP2 (MIM 602143) are activators of p53.[supplied by OMIM, Mar 2008].

Pfam Domains

Ank_2aa 631–723UCSCAnkyrin repeats (3 copies)
SH3_9aa 765–815UCSCVariant SH3 domain

Gene Aliases

HGNC Name

protein phosphatase 1 regulatory subunit 13 like

HGNC Alias Symbol

IASPP

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
4 papers
NM_006663.4
p.K23*
c.67A>T
Surrounding Variants
1 paper
NM_006663.4
p.G62A
c.185G>C
1 paper
NM_006663.4
p.E4D
c.12G>T
1 paper
NM_006663.4
p.F79C
c.236T>G
1 paper
NM_006663.4
p.S100P
c.298T>C
1 paper
NM_006663.4
p.S113Y
c.338C>A
1 paper
NM_006663.4
p.R122H
c.365G>A
1 paper
NM_006663.4
p.L125I
c.373C>A
1 paper
NM_006663.4
p.P129P
c.387G>A
1 paper
NM_006663.4
p.A131T
c.391G>A
1 paper
NM_006663.4
p.R160W
c.478C>T
1 paper
NM_006663.4
p.G162R
c.484G>C
1 paper
NM_006663.4
p.G162R
c.484G>A
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