Varaico: Literature-Extracted Genetic Variants

PPP1R15B

78 papers

RefSeq Summary

This gene encodes a protein phosphatase I-interacting protein that promotes the dephosphorylation of eukaryotic translation initiation factor 2A to regulate translation under conditions of cellular st...

Pfam Domains

CReP_Naa 1–410UCSCeIF2-alpha phosphatase phosphorylation constitutive repressor

PP1c_bdgaa 469–699UCSCPhosphatase-1 catalytic subunit binding region

Gene Aliases

HGNC Name

protein phosphatase 1 regulatory subunit 15B

HGNC Alias Symbol

FLJ14744

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_032833.5

p.H635_V636delFs

c.1905_1908del4

Surrounding Variants

1 paper

NM_032833.5

p.H635fs

c.1903_1904fs

1 paper

NM_032833.5

p.S629C

c.1886C>G

1 paper

NM_032833.5

p.S622W

c.1865C>G

1 paper

NM_032833.5

p.V609_G613del0

c.1827_1838del12

3 papers

NM_032833.5

p.K589E

c.1765A>G

1 paper

NM_032833.5

p.G584A

c.1751G>C

1 paper

NM_032833.5

p.Q576H

c.1728A>C

1 paper

NM_032833.5

p.E469D

c.1407A>T

1 paper

NM_032833.5

p.E469D

c.1407A>C

1 paper

NM_032833.5

p.S461C

c.1381A>T

1 paper

NM_032833.5

p.E453_D454del2

c.1357_1361del6

2 papers

NM_032833.5

p.N423D

c.1267A>G