Varaico: Literature-Extracted Genetic Variants

PPP1R15B

78 papers

RefSeq Summary

This gene encodes a protein phosphatase I-interacting protein that promotes the dephosphorylation of eukaryotic translation initiation factor 2A to regulate translation under conditions of cellular st...

Pfam Domains

CReP_Naa 1–410UCSCeIF2-alpha phosphatase phosphorylation constitutive repressor

PP1c_bdgaa 469–699UCSCPhosphatase-1 catalytic subunit binding region

Gene Aliases

HGNC Name

protein phosphatase 1 regulatory subunit 15B

HGNC Alias Symbol

FLJ14744

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_032833.5

p.E469D

c.1407A>C

Surrounding Variants

1 paper

NM_032833.5

p.E469D

c.1407A>T

1 paper

NM_032833.5

p.S461C

c.1381A>T

1 paper

NM_032833.5

p.E453_D454del2

c.1357_1361del6

2 papers

NM_032833.5

p.N423D

c.1267A>G

1 paper

NM_032833.5

p.A417V

c.1250C>T

1 paper

NM_032833.5

p.S416T

c.1246T>A

1 paper

NM_032833.5

p.E395D

c.1185G>T

1 paper

NM_032833.5

p.E395D

c.1185G>C

1 paper

NM_032833.5

p.P391H

c.1172C>A

1 paper

NM_032833.5

p.E389K

c.1165G>A

1 paper

NM_032833.5

p.E379D

c.1137G>T

1 paper

NM_032833.5

p.E379D

c.1137G>C