Varaico: Literature-Extracted Genetic Variants

PPP1R15B

78 papers

RefSeq Summary

This gene encodes a protein phosphatase I-interacting protein that promotes the dephosphorylation of eukaryotic translation initiation factor 2A to regulate translation under conditions of cellular st...

Pfam Domains

CReP_Naa 1–410UCSCeIF2-alpha phosphatase phosphorylation constitutive repressor

PP1c_bdgaa 469–699UCSCPhosphatase-1 catalytic subunit binding region

Gene Aliases

HGNC Name

protein phosphatase 1 regulatory subunit 15B

HGNC Alias Symbol

FLJ14744

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_032833.5

p.S308N

c.923G>A

Surrounding Variants

1 paper

NM_032833.5

p.P314S

c.940C>T

1 paper

NM_032833.5

p.I293del1

c.877_879delAAT

1 paper

NM_032833.5

p.P269S

c.805C>T

1 paper

NM_032833.5

p.P269A

c.805C>G

1 paper

NM_032833.5

p.Q268H

c.804G>T

1 paper

NM_032833.5

p.Q268H

c.804G>C

1 paper

NM_032833.5

p.A349V

c.1046C>T

1 paper

NM_032833.5

p.A350V

c.1049C>T

1 paper

NM_032833.5

p.D263V

c.788A>T

1 paper

NM_032833.5

p.E262K

c.784G>A

1 paper

NM_032833.5

p.R261K

c.782G>A

2 papers

NM_032833.5

p.S360F

c.1079C>T