Varaico: Literature-Extracted Genetic Variants

PPP1R15B

78 papers

RefSeq Summary

This gene encodes a protein phosphatase I-interacting protein that promotes the dephosphorylation of eukaryotic translation initiation factor 2A to regulate translation under conditions of cellular st...

Pfam Domains

CReP_Naa 1–410UCSCeIF2-alpha phosphatase phosphorylation constitutive repressor

PP1c_bdgaa 469–699UCSCPhosphatase-1 catalytic subunit binding region

Gene Aliases

HGNC Name

protein phosphatase 1 regulatory subunit 15B

HGNC Alias Symbol

FLJ14744

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_032833.5

p.P225L

c.674C>T

Surrounding Variants

2 papers

NM_032833.5

p.P225delFs

c.674delG

1 paper

NM_032833.5

p.L222_N224delFs

c.665_671del7

1 paper

NM_032833.5

p.V218V

c.654G>C

1 paper

NM_032833.5

p.R233G

c.697A>G

1 paper

NM_032833.5

p.G243E

c.728G>A

1 paper

NM_032833.5

p.P204_S205delFs

c.610_613del4

1 paper

NM_032833.5

p.S205F

c.614C>T

1 paper

NM_032833.5

p.E246Q

c.736G>C

1 paper

NM_032833.5

p.V247A

c.740T>C

1 paper

NM_032833.5

p.L200I

c.598C>A

1 paper

NM_032833.5

p.T254_P255insFs

c.762_763insGG

1 paper

NM_032833.5

p.E256K

c.766G>A