Varaico: Literature-Extracted Genetic Variants

PPP1R15B

78 papers

RefSeq Summary

This gene encodes a protein phosphatase I-interacting protein that promotes the dephosphorylation of eukaryotic translation initiation factor 2A to regulate translation under conditions of cellular st...

Pfam Domains

CReP_Naa 1–410UCSCeIF2-alpha phosphatase phosphorylation constitutive repressor

PP1c_bdgaa 469–699UCSCPhosphatase-1 catalytic subunit binding region

Gene Aliases

HGNC Name

protein phosphatase 1 regulatory subunit 15B

HGNC Alias Symbol

FLJ14744

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_032833.5

p.Q150*

c.448C>T

Surrounding Variants

1 paper

NM_032833.5

p.S152*

c.455C>A

1 paper

NM_032833.5

p.Y151_S152delFs

c.453_454delAG

1 paper

NM_032833.5

p.L143_E144del2

c.427_431del6

1 paper

NM_032833.5

p.P139H

c.416C>A

1 paper

NM_032833.5

p.T137S

c.410C>G

1 paper

NM_032833.5

p.T137S

c.409A>T

1 paper

NM_032833.5

p.S135L

c.404C>T

1 paper

NM_032833.5

p.S165G

c.493A>G

1 paper

NM_032833.5

p.P134S

c.400C>T

1 paper

NM_032833.5

p.D133V

c.398A>T

1 paper

NM_032833.5

p.D130D

c.390C>T

1 paper

NM_032833.5

p.D130N

c.388G>A