Varaico: Literature-Extracted Genetic Variants

PPP1R15B

78 papers

RefSeq Summary

This gene encodes a protein phosphatase I-interacting protein that promotes the dephosphorylation of eukaryotic translation initiation factor 2A to regulate translation under conditions of cellular st...

Pfam Domains

CReP_Naa 1–410UCSCeIF2-alpha phosphatase phosphorylation constitutive repressor

PP1c_bdgaa 469–699UCSCPhosphatase-1 catalytic subunit binding region

Gene Aliases

HGNC Name

protein phosphatase 1 regulatory subunit 15B

HGNC Alias Symbol

FLJ14744

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_032833.5

p.V81M

c.241G>A

Surrounding Variants

1 paper

NM_032833.5

p.K80R

c.239A>G

1 paper

NM_032833.5

p.L78P

c.233T>C

1 paper

NM_032833.5

p.S85S

c.255C>T

1 paper

NM_032833.5

p.P75S

c.223C>T

1 paper

NM_032833.5

p.M91V

c.271A>G

1 paper

NM_032833.5

p.M91R

c.272T>G

1 paper

NM_032833.5

p.Q86_T94delFs

c.256_281del26

1 paper

NM_032833.5

p.L97P

c.290T>C

1 paper

NM_032833.5

p.Y62F

c.185A>T

1 paper

NM_032833.5

p.Q55*

c.163C>T

1 paper

NM_032833.5

p.P48delFs

c.143_144delGG

1 paper

NM_032833.5

p.P48fs

c.142_143fs