Varaico: Literature-Extracted Genetic Variants

Gene:PPP2CA
Variant:p.Y265C

PPP2CA

93 papers

RefSeq Summary

This gene encodes the phosphatase 2A catalytic subunit. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. ...

Pfam Domains

Metallophosaa 50–245UCSCCalcineurin-like phosphoesterase

Gene Aliases

HGNC Name

protein phosphatase 2 catalytic subunit alpha

HGNC Alias Symbols

PP2Calpha; PP2AC

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
8 papers
NM_002715.4
p.Y265C
c.794A>G
Surrounding Variants
1 paper
NM_002715.4
p.T258P
c.772A>C
1 paper
NM_002715.4
p.R254Q
c.761G>A
1 paper
NM_002715.4
p.R254G
c.760C>G
1 paper
NM_002715.4
p.E277*
c.829G>T
1 paper
NM_002715.4
p.Y248_N249delFs
c.744_745delTA
1 paper
NM_002715.4
p.Y248*
c.744T>G
1 paper
NM_002715.4
p.Y248*
c.744T>A
1 paper
NM_002715.4
p.G247A
c.740G>C
2 papers
NM_002715.4
p.Q242E
c.724C>G
1 paper
NM_002715.4
p.H241R
c.722A>G
6 papers
NM_002715.4
p.D223V
c.668A>T
6 papers
NM_002715.4
p.D223H
c.667G>C
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."