Varaico: Literature-Extracted Genetic Variants

Gene:PPP2CA
Variant:p.F146fs

PPP2CA

93 papers

RefSeq Summary

This gene encodes the phosphatase 2A catalytic subunit. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. ...

Pfam Domains

Metallophosaa 50–245UCSCCalcineurin-like phosphoesterase

Gene Aliases

HGNC Name

protein phosphatase 2 catalytic subunit alpha

HGNC Alias Symbols

PP2Calpha; PP2AC

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
3 papers
NM_002715.4
p.F146fs
c.436_437fs
Surrounding Variants
2 papers
NM_002715.4
p.F146L
c.436T>C
2 papers
NM_002715.4
p.F146fs
c.436_437fs
2 papers
NM_002715.4
p.F146L
c.438T>G
2 papers
NM_002715.4
p.F146L
c.438T>A
2 papers
NM_002715.4
p.F146delFs
c.438delA
1 paper
NM_002715.4
p.R135T
c.404G>C
1 paper
NM_002715.4
p.V159E
c.476T>A
1 paper
NM_002715.4
p.D160N
c.478G>A
5 papers
NM_002715.4
p.D131H
c.391G>C
1 paper
NM_002715.4
p.Q162_I163Splc
c.486+4T>C
1 paper
NM_002715.4
p.G128R
c.382G>C
1 paper
NM_002715.4
p.Y127*
c.381T>G
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."